Cdc37 Antibody

CAT: 0800-R31256Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-R31256Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Hsp90 co-chaperone Cdc37 is a protein that in humans is encoded by the CDC37 gene. The protein encoded by this gene is highly similar to cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This gene is mapped to 19p13.2. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is though to play a critical role in directing Hsp90 to its target kinases.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q16543
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the C-terminus of human Cdc37 (DPLLEAVPKTGDEKDV) was used as the immunogen for this Cdc37 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the Cdc37 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Cdc37 antibody is available for research use only.
Storage Conditions
After reconstitution, the Cdc37 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the Cdc37 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of Cdc37 antibody and 1. Jurkat, 2. 293T cell lysate. Expected/observed molecular weight 44~50kDa.

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PT-A00871-01CDC37 Antibody

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