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Cystatin A Antibody

CAT: 0800-R31217Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31217Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cystatin A, also called Stefin A, is a protein that in humans is encoded by the CSTA gene. Cystatin A is a cysteine proteinase inhibitor that belongs to family 1 of the cystatin superfamily. This gene was assigned to human chromosome 3q21.1. This is an intracellular thiol proteinase inhibitor. The protein plays an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis and has been proposed as prognostic and diagnostic tools for cancer.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL
UniProt
P01040
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the C-terminus of human Cystatin A (NEDLVLTGYQVDKN) was used as the immunogen for this Cystatin A antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the Cystatin A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Cystatin A antibody is available for research use only.
Storage Conditions
After reconstitution, the Cystatin A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the Cystatin A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic
Image Legend
Western blot testing of Cystatin A antibody and human A431 cell lysate. Predicted molecular weight ~11 kDa.

UniProtKB · P01040

Cystatin-A

CYTA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01040
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CSTA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q6IB90
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Acetylation

Biological process

Cell adhesion

Cellular component

Cytoplasm

Disease

Ichthyosis

Molecular function

Protease inhibitorThiol protease inhibitor
Product Datasheet
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