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RGS3 Antibody

CAT: 0800-R31161Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31161Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Regulator of G Protein Signaling 3 is a protein that in humans is encoded by the RGS3 gene. Chatterjee et al. (1997) studied RGS3, the largest member of the RGS family then identified. Mouse Pdz-Rgs3 can mediate signaling from the ephrin-B cytoplasmic tail. By radiation hybrid mapping, Chatterjee et al. (1997) assigned the gene to chromosome 9q31-q33. Lu et al. (2001) showed that Sdf1, a chemokine with a G protein-coupled receptor, and Bdnf are chemoattractants for cerebellar granule cells, and that Sdf1 chemoattraction is selectively inhibited by soluble ephrin-B receptor. This inhibition could be blocked by a truncated Pdz-Rgs3 protein lacking the RGS domain.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
Q9DC04
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An amino acid sequence from the C-terminus of mouse Regulator of G Protein Signaling 3 (DSYTREHTKENLQSITR) was used as the immunogen for this RGS3 antibody (100% rat homology) .
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the RGS3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This RGS3 antibody is available for research use only.
Storage Conditions
After reconstitution, the RGS3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the RGS3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of RGS3 antibody and Lane 1: rat testis; 2: (r) brain; 3: (r) spleen; 4: human HeLa; 5: (h) U87 cell lysate

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