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LAT2 Antibody

CAT: 0800-R31149Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31149Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Linker for Activation of T Cells Family, Member 2, also known as LAB or NTAL , is a protein that in humans is encoded by the LAT2 gene. By genomic sequence analysis, Doyle et al. (2000) mapped the gene to chromosome 7q11.23. They noted that the flanking genes are highly conserved between mouse and human. By immunoprecipitation and immunoblot analysis, Brdicka et al. (2002) found that the protein associated with GRB2, SOS1, and GAB1 after B-cell receptor activation. Janssen et al. (2003) determined that phosphorylation of LAT2 is likely mediated by SYK upon B-cell receptor stimulation. Binding analysis indicated associations with GRB2, and, indirectly, with PLCG1 and PLCG2.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q9GZY6
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the N-terminus of human Linker for Activation of T Cells Family, Member 2 (KRSEKIYQQRSLRED) was used as the immunogen for this LAT2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the LAT2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This LAT2 antibody is available for research use only.
Storage Conditions
After reconstitution, the LAT2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the LAT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of LAT2 antbody; Lane 1: Recombinant human protein 10ng; 2: 5ng; 3: 2.5ng; 4: 1.25ng

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