TRAF1 Antibody

• Description:

  TNF Receptor-Associated Factor 1, also called EBI6, is a protein that in humans is encoded by the TRAF1 gene. The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. Siemienski et al. (1997) used fluorescence in situ hybridization to map the gene to 9q33-q34. Mosialos et al. (1995) found that LMP1, the EBV-transforming protein, specifically associates with LAP1 (TRAF3) or TRAF1 in B lymphoblasts. LMP1 expression redirects LAP1 and TRAF1 from scattered cytoplasmic structures to LMP1 plasma membrane patches. Both LAP1 and TRAF1 associated with the cytoplasmic domain of p80/TNFR2 in vivo.

• Specifications:

  Western blot: 0.5-1 µg/mL

• UniProt:

  Q13077

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  An amino acid sequence from the middle region of human TNF Receptor-Associated Factor 1 (HQSQLDRERILSLEQR) was used as the immunogen for this TRAF1 antibody.

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  WB

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal

• Reconstitution:

  After reconstitution, the TRAF1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations:

  This TRAF1 antibody is available for research use only.

• Storage Conditions:

  After reconstitution, the TRAF1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation:

  0.5 mg/mL if reconstituted with 0.2ml sterile DI water

• Applications Notes:

  The stated application concentrations are suggested starting amounts. Titration of the TRAF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of TRAF1 antbody and recombinant human protein, 30.6KD with tag; Lane 1: 5ng; 2: 2.5ng; 3: 1.25ng