LTK Antibody

• Description:

  Leukocyte tyrosine kinase, also known as TYK1, is an enzyme that in humans is encoded by the LTK gene. The protein encoded by this gene is a member of the ALK/LTK receptor family of receptor tyrosine kinases (RTKs) whose ligand is unknown. Toyoshima et al. (1993) cloned a set of cDNAs representing differently spliced human LTK mRNAs. Liao et al. (1996) found that the mouse Ltk gene is closely linked to the Tyro3 gene which maps to mouse chromosome 2. Thus, the gene produces not only the putative receptor tyrosine kinase for an unknown ligand but also multiple protein products that may have different functions.

• Specifications:

  Western blot: 0.5-1 µg/mL

• UniProt:

  P29376

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  An amino acid sequence from the C-terminus of human Leukocyte tyrosine kinase (RGLQPQNLWNPTYRS) was used as the immunogen for this LTK antibody.

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  WB

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal

• Reconstitution:

  After reconstitution, the LTK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations:

  This LTK antibody is available for research use only.

• Storage Conditions:

  After reconstitution, the LTK antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation:

  0.5 mg/mL if reconstituted with 0.2ml sterile DI water

• Applications Notes:

  The stated application concentrations are suggested starting amounts. Titration of the LTK antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of LTK antibody and human recombinant protein; Lane 1: 10ng; 2: 5ng; 3: 2.5ng; 4: 1.25ng