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HSPB1 Antibody

CAT: 0800-R30899Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30899Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HSPB1 (Heat shock 27kDa protein 1) is a protein that in humans is encoded by the HSPB1 gene. Stock et al.(2003) used FISH to map the HSP27 gene to 7q11.23. The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).
CAS Number
9007-83-4
UniProt
P04792
Host
Rabbit
Immunogen
An amino acid sequence from the middle region of human HSP27 (KHEERQDEHGYISRCFTR) was used as the immunogen for this HSPB1 antibody (100% homologous in human, mouse and rat).
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, ICC
Format
Antigen affinity purified
Buffer
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Reconstitution
After reconstitution, the HSPB1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This HSPB1 antibody is available for research use only.

UniProtKB · P04792

Heat shock protein beta-1

HSPB1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04792
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HSPB1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
HspB1
EC number
—
Processing
—
Secondary accessions
B2R4N8, Q6FI47, Q96C20, Q96EI7, Q9UC31, Q9UC34, Q9UC35, Q9UC36
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationMethylationPhosphoprotein

Molecular function

Chaperone

Disease

Charcot-Marie-Tooth diseaseDisease variantNeurodegenerationNeuropathy

Cellular component

CytoplasmCytoskeletonNucleus

Biological process

Host-virus interactionStress response

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