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LASP1 Antibody

CAT: 0800-R30889Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30889Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LIM and SH3 domain protein 1 is a protein that in humans is encoded by the LASP1 gene. This gene encodes a member of a LIM protein subfamily which is characterized by a LIM motif and a domain of Src homology region 3. This protein functions as an actin-binding protein and possibly in cytoskeletal organization. LASP1 has been shown to interact with Zyxin. Northern blot analysis revealed that LASP1 mRNA was expressed at a basal level in all normal tissues examined and overexpressed in 8% of primary breast cancers. In most of these cancers, LASP1 and ERBB2 were simultaneously overexpressed.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
Q14847
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the C-terminus of human LASP1 (YRRPLEQQQPHHIPTSA) was used as the immunogen for this LASP1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the LASP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This LASP1 antibody is available for research use only.
Storage Conditions
After reconstitution, the LASP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the LASP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of LASP1 antibody and Lane 1: HeLa; 2: MCF-7 cell lysate. Predicted molecular weight: 30kDa.

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