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APLP2 Antibody

CAT: 0800-R30739Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30739Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Amyloid beta (A4) precursor-like protein 2, also known as CDEBP, is a protein that in humans is encoded by the APLP2 gene. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. Along with APLP1, it is an important modulator of glucose and insulin homeostasis. APLP2 associates with antigen presentation molecules like MHC class I molecules and regulates their surface expression by enhancing endocytosis.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q06481
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An amino acid sequence from the C-terminus of human APLP2 (EEKVINSKNKVDENMVID) was used as the immunogen for this APLP2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the APLP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This APLP2 antibody is available for research use only.
Storage Conditions
After reconstitution, the APLP2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the APLP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of 1) human SH-SY5Y, 2) human HepG2, 3) human HeLa, 4) rat brain and 5) mouse brain tissue lysate with APLP2 antibody. Predicted molecular weight ~87 kDa, the glycosylated full length and truncated form can be observed at ~120 kDa and ~95 kDa, the CS-GAG modified form can be observed at 130-170 kDa and homodimers and heterodimers may be observed at over 200 kDa.

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