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IL-2 Receptor Antibody (beta subunit)

CAT: 0800-R30696Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30696Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Interleukin 2 receptor beta, also called CD122, is a protein that in humans is encoded by the IL2RB gene. The gene represents the beta subunit and is a type I membrane protein. The IL2RB gene contains 10 exons spanning about 24.3 kb and that the gene product is encoded by exons 2-10. IL-2 receptor is present in three forms with respect to binding ability to IL-2: high, intermediate, and low affinity forms. Analysis of mutants of the beta chain of the IL-2 receptor reveals that the granulocyte and monocyte differentiation signals are triggered by different cytoplasmic domains, showing that the signaling pathways responsible for these unique developmental outcomes are separable.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P14784
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids 117-135 (RVMAIQDFKPFENLRLMAP-human) of the beta subunit were used as the immunogen for this IL-2 Receptor antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the IL-2 Receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This IL-2 Receptor antibody is available for research use only.
Storage Conditions
After reconstitution, the IL-2 Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the IL-2 Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of IL-2 Receptor antibody and Lane 1: PANC cell lysate ; 2: HeLa cell lysate. Expected molecular weight ~61 kDa (unmodified), 70-75 kDa (glycosylated) .

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