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INDOL1 Antibody

CAT: 0800-R30692Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30692Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IDO2 (Indoleamine 2,3-dioxygenase 2), also called Indoleamine 2,3-dioxygenase-like 1, is an enzyme encoded by the INDOL1 gene which metabolizes tryptophan in the kynurenine pathway. By genomic sequence analysis, the gene is mapped on chromosome 8p12 just downstream of the INDO gene. And its exact cytogenetic location is 8p11.21. By database analysis using INDO as probe, followed by RT-PCR of total RNA from various tissues, IDO2 is cloned by human and mouse INDOL1. INDOL1 catabolizes tryptophan as determined by Kyn production, but unlike INDO, is inhibited by D-1-methyl-tryptophan (D-1MT) but not the L-1MT stereoisomer.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q6ZQW0
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids 1-20 (MLHFHYYDTSNKIMEPHRPN-human) were used as the immunogen for this INDOL1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the INDOL1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This INDOL1 antibody is available for research use only.
Storage Conditions
After reconstitution, the INDOL1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the INDOL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of INDOL1 antibody and Lane 1: human A549; 2: human placenta; 3: human A431 cell lysate. Expected molecular weight: ~47 kDa.
Product Datasheet
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