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Eotaxin Antibody

CAT: 0800-R30607Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30607Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Eotaxin, also known as CCL11 (Chemokine (C-C motif) ligand 11), a small cytokine belonging to the CC chemokine family. Eotaxin selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of Eotaxin are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which Eotaxinis a ligand include CCR2, CCR3 and CCR5. However, it has been found that eotaxin-1 (CCL11) has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3. The gene for human Eotaxin is encoded on three exons and is located on chromosome 17q12.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P48298
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
An amino acid sequence from the C-terminus of mouse Eotaxin (CADPKKKWVQDATKHLDQKLQ) was used as the immunogen for this Eotaxin antibody (100% rat homology) .
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the Eotaxin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Eotaxin antibody is available for research use only.
Storage Conditions
After reconstitution, the Eotaxin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the Eotaxin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of Eotaxin antibody and Lane 1: recombinant mouse protein 10ng; 2: 5ng; 3: 2.5ng; 4: 1.25ng

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