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I-309 Antibody

CAT: 0800-R30600Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30600Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Chemokine (C-C motif) ligand 1, also called I-309, is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P22362
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the C-terminus of human I-309 (WVQRHRKMLRHCPSKRK) was used as the immunogen for this I-309 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the I-309 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This I-309 antibody is available for research use only.
Storage Conditions
After reconstitution, the I-309 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the I-309 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of I-309 antibody and Lane 1: SCG; 2: COLO320; 3: Jurkat cell lysate. Expeced size ~11KD, observed size ~17KD

UniProtKB · P22362

C-C motif chemokine 1

CCL1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P22362
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CCL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2R5G9, Q2M309
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Chemotaxis

Molecular function

Cytokine

PTM

Disulfide bondGlycoprotein

Cellular component

Secreted

Domain

Signal

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