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GAP43 Antibody

CAT: 0800-R30214Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30214Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Growth Associated Protein-43 (GAP-43), also known as nerve growth-related growth peptide GAP43, shares a high degree of homology between the sequence of the human gene and the rat gene. GAP-43 is considered a crucial component of an effective regenerative response in the nervous system. Somatic cell hybrids demonstrate localization of the GAP-43 gene to human chromosome 3 and to mouse chromosome 16. GAP-43 has been termed a growth or plasticity protein because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration. GAP-43 regulates growth of axons and modulates the formation of new connections.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
P17677
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids KPKESARQDEGKEEEPEADQEHA were used as the immunogen for this GAP43 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the GAP43 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This GAP43 antibody is available for research use only.
Storage Conditions
After reconstitution, the GAP43 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the GAP43 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of GAP43 antibody and Lane 1: U87; 2: rat brain; 3: mouse brain; Predicted/observed molecular weight: ~43kDa.
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