Products for Research Use Only
RegisterLogin

GJB2 Antibody

CAT: 0800-R30199Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-R30199Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Connexin 26 (CX26), also known as GAP junction protein beta2 (GJB2) . Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The 3-prime untranslated region of the CX26 transcript contains a putative mRNA instability sequence. The deduced 226-amino acid protein has a calculated molecular mass of about 26 kD. CX26 shares 92.5% identity with rat Cx26. connexin 26 (GJB2) is assigned to human chromosome 13q11-q12 .Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response. Connexin 26 gene (GJB2) mutation modulates the severity of hearing loss associated with the 1555A-G mitochondrial mutation.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P29033
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An amino acid sequence from the N-terminus of human GJB2 (MDWGTLQTILGGVNKH) was used as the immunogen for this GJB2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the GJB2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This GJB2 antibody is available for research use only.
Storage Conditions
After reconstitution, the GJB2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the GJB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of GJB2 antibody and rat liver tissue lysate. Predicted molecular weight: ~26kDa.

Related Products

CatalogName
RQ6770Connexin 26 Antibody / GJB2
RQ4180Connexin 32 Antibody / GJB1
V3305-100UGConnexin 32 Antibody / GJB1
V3304SAF-100UGConnexin 32 Antibody / GJB1
V3306-20UGConnexin 32 Antibody / GJB1
V3304-100UGConnexin 32 Antibody / GJB1
V3306SAF-100UGConnexin 32 Antibody / GJB1
V3305SAF-100UGConnexin 32 Antibody / GJB1
V3306-100UGConnexin 32 Antibody / GJB1
V3305-20UGConnexin 32 Antibody / GJB1

Alternative Products

CatalogName
70R-1685GJB2 antibody

Popular Products