Spectrin Antibody (alpha and beta)

Spectrin Antibody (alpha and beta)

• Description: Spectrin, the predominant component of the membrane skeleton of the red cell, is essential in determining the properties of the membrane including its shape and deformability. It consists of 2 nonidentical subunits, alpha and beta. Spectrin is present in the red cell membrane in a tetrameric or possibly higher polymeric form through head-to-head self-association of heterodimers that are linked by actin polymers and protein 4.1 to form a 2-dimensional network. Non-erythroid spectrin gene is mapped to human chromosome 2. Spectrin mutations cause spinocerebellar ataxia type 5.
• CAS Number: 9007-83-4
• Host: Mouse
• Immunogen: Human erythrocyte spectrin was used as the immunogen for this Spectrin antibody (alpha and beta).
• Clonality: Monoclonal
• Isotype: IgG1
• Applications: WB
• Format: Ascites
• Buffer: 0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS
• Reconstitution: After reconstitution, the Spectrin antibody (alpha and beta) can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
• Limitations: This Spectrin antibody (alpha and beta) is available for research use only.