MAP3K13 Antibody

• Description:

  Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.

• Specifications:

  Western blot: 1:250-1:500, Immunofluorescence: 1:50-1:100

• UniProt:

  O43283

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 52-305 from the human protein was used as the immunogen for the MAP3K13 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgM

• Clone:

  810CT26.6.1.1

• Applications:

  WB, IF

• Purity:

  Purified

• Format:

  Purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the MAP3K13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This MAP3K13 antibody is available for research use only.

• Storage Conditions:

  Aliquot the MAP3K13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  The stated application concentrations are suggested starting points. Titration of the MAP3K13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Location:

  Cytoplasmic

• Image Legend:

  Immunofluorescent staining of human NCI-H460 cells with MAP3K13 antibody (green), DAPI nuclear stain (blue) and anti-Actin (red) .