Beta-nerve growth factor Antibody / NGF

• Description:

  NGFB is a member of the NGF-beta family. It is a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in the gene encoding NGFB have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of the gene's expression is associated with allergic rhinitis.

• Specifications:

  Immunofluorescence: 1:10-1:50, Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:10-1:50, Western blot: 1:500-1:1000

• UniProt:

  P01138

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 84-115 from the human protein was used as the immunogen for the Beta-nerve growth factor antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  IF, FACS, IHC-P, WB

• Purity:

  Purified

• Format:

  Purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the Beta-nerve growth factor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This Beta-nerve growth factor antibody is available for research use only.

• Storage Conditions:

  Aliquot the Beta-nerve growth factor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  The stated application concentrations are suggested starting points. Titration of the Beta-nerve growth factor antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Location:

  Cytoplasmic, secreted

• Image Legend:

  IHC testing of FFPE human brain tissue with Beta-nerve growth factor antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.