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Vitronectin Antibody / VTN

CAT: 0800-F54930-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F54930-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vitronectin is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1:10-1:50, Western blot: 1:1000-1:2000, Flow cytometry: 1:25 (1x10e6 cells)
UniProt
P04004
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 65-93 from the human protein was used as the immunogen for the Vitronectin antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P, WB, FACS
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Vitronectin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Vitronectin antibody is available for research use only.
Storage Conditions
Aliquot the Vitronectin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the Vitronectin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic, membrane
Image Legend
IHC testing of FFPE human lung carcinoma tissue with Vitronectin antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

UniProtKB · P04004

Vitronectin

VTNC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04004
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
VTN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
VN
EC number
—
Processing
Precursor
Secondary accessions
B2R7G0, P01141, Q9BSH7
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Cell adhesion

PTM

Disulfide bondGlycoproteinPhosphoproteinSulfation

Molecular function

Heparin-binding

Domain

RepeatSignal

Cellular component

Secreted

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