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SRP72 Antibody

CAT: 0800-F54900-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F54900-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. It binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.
CAS Number
9007-83-4
Specifications
Immunofluorescence: 1:25, Immunohistochemistry (FFPE) : 1:25, Flow cytometry: 1:25 (1x10e6 cells), Western blot: 1:500-1:2000
UniProt
O76094
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 119-148 from the human protein was used as the immunogen for the SRP72 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IF, IHC-P, FACS, WB
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the SRP72 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SRP72 antibody is available for research use only.
Storage Conditions
Aliquot the SRP72 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the SRP72 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic
Image Legend
Western blot testing of human 1) HeLa and 2) K562 cell lysate with SRP72 antibody. Predicted molecular weight: 68-75 kDa.

UniProtKB · O76094

Signal recognition particle subunit SRP72

SRP72_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O76094
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SRP72
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
SRP72
EC number
—
Processing
—
Secondary accessions
G5E9Z8, Q7Z3C0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmEndoplasmic reticulumSignal recognition particle

Disease

Disease variant

Domain

RepeatTPR repeat

Molecular function

Ribonucleoprotein
Product Datasheet
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