Transthyretin Antibody / TTR / Prealbumin

Transthyretin Antibody / TTR / Prealbumin

• Description: Transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.
• CAS Number: 9007-83-4
• UniProt: P02766
• Host: Rabbit
• Immunogen: A portion of amino acids 71-98 from the human protein was used as the immunogen for the Transthyretin antibody.
• Clonality: Polyclonal
• Isotype: Ig
• Applications: IF, WB, IHC-P, FACS
• Format: Purified
• Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Reconstitution: Aliquot the Transthyretin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This Transthyretin antibody is available for research use only.