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KLF11 Antibody / TIEG2

CAT: 0800-F54867-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F54867-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TIEG2 is a transcription factor. The protein activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. It represses transcription of SMAD7 which enhances TGF-beta signaling. It induces apoptosis.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1:50-1:100, Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunofluorescence: 1:10-1:50, Western blot: 1:500-1:1000
UniProt
O14901
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 7-36 from the human protein was used as the immunogen for the KLF11 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC-P, FACS, IF, WB
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the KLF11 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This KLF11 antibody is available for research use only.
Storage Conditions
Aliquot the KLF11 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the KLF11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Nuclear
Image Legend
Western blot testing of human K562 cell lysate with KLF11 antibody. Expected molecular weight: 55-65 kDa.

UniProtKB · O14901

Krueppel-like factor 11

KLF11_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O14901
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KLF11
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4DZE7, Q9EPF4
Protein keywords

Molecular function

ActivatorDNA-bindingRepressor

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisTranscriptionTranscription regulation

Disease

Diabetes mellitusDisease variant

Ligand

Metal-bindingZinc

Cellular component

Nucleus

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

Domain

RepeatZinc-finger
Product Datasheet
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