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ADCYAP1 Antibody / PACAP

CAT: 0800-F54833-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F54833-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ADCYAP1 is adenylate cyclase activating polypeptide 1. Mediated by adenylate cyclase activating polypeptide 1 receptors, this polypeptide stimulates adenylate cyclase and subsequently increases the cAMP level in target cells. Adenylate cyclase activating polypeptide 1 is not only a hypophysiotropic hormone, but also functions as a neurotransmitter and neuromodulator. In addition, it plays a role in paracrine and autocrine regulation of certain types of cells. This gene encodes three different mature peptides, including two isotypes, a shorter form and a longer form.
CAS Number
9007-83-4
Specifications
Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunofluorescence: 1:10-1:50, Immunohistochemistry (FFPE) : 1:10-1:50, Western blot: 1:500-1:1000
UniProt
P18509
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 148-176 from the human protein was used as the immunogen for the ADCYAP1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
FACS, IF, IHC-P, WB
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the ADCYAP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ADCYAP1 antibody is available for research use only.
Storage Conditions
Aliquot the ADCYAP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the ADCYAP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
IHC testing of FFPE human testis tissue with ADCYAP1 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

UniProtKB · P18509

Pituitary adenylate cyclase-activating polypeptide

PACA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P18509
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ADCYAP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PACAP
EC number
—
Processing
Precursor
Secondary accessions
B2R7N4, Q52LQ0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AmidationCleavage on pair of basic residues

Molecular function

Hormone

Biological process

Neurogenesis

Cellular component

Secreted

Domain

Signal
Product Datasheet
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