ERLIN2 Antibody

• Description:

  Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) . Also involved in ITPR1 degradation by the ERAD pathway.

• Specifications:

  Western blot: 1:500-1:1000

• UniProt:

  O94905

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A portion of amino acids 307-333 from the human protein was used as the immunogen for the ERLIN2 antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB

• Purity:

  Antigen affinity purified

• Format:

  Purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the ERLIN2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This ERLIN2 antibody is available for research use only.

• Storage Conditions:

  Aliquot the ERLIN2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  The stated application concentrations are suggested starting points. Titration of the ERLIN2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of 1) human 293T, 2) human A431, 3) mouse C2C12, 4) mouse NIH 3T3, 5) human breast and 6) human placenta lysate with ERLIN2 antibody. Predicted molecular weight: ~38 kDa, routinely observed at ~43 kDa.