BIRC3 Antibody

• Description :

  The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq].

• CAS Number :

  9007-83-4

• Specifications :

  Western blot: 1:500-1:2000, Immunofluorescence: 1:25, Immunohistochemistry (FFPE) : 1:25

• UniProt :

  Q13489

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  A portion of amino acids 59-88 from the human protein was used as the immunogen for the BIRC3 antibody.

• Clonality :

  Polyclonal

• Isotype :

  Ig

• Applications :

  WB, IF, IHC-P

• Purity :

  Antigen affinity purified

• Format :

  Purified

• Buffer :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution :

  Aliquot the BIRC3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations :

  This BIRC3 antibody is available for research use only.

• Storage Conditions :

  Aliquot the BIRC3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes :

  The stated application concentrations are suggested starting points. Titration of the BIRC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Location :

  Cytoplasmic, nuclear

• Image Legend :

  Western blot testing of 1) non-transfected and 2) transfected 293 cell lysate with BIRC3 antibody. Predicted molecular weight ~68 kDa.