GAD65 Antibody / GAD2
CAT:
800-F54577-0.4ML
Size:
0.4 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
GAD65 Antibody / GAD2
- Description: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
- CAS Number: 9007-83-4
- UniProt: Q05329
- Host: Rabbit
- Immunogen: A portion of amino acids 109-138 from the human protein was used as the immunogen for the GAD2 antibody.
- Clonality: Polyclonal
- Isotype: Ig
- Applications: WB, IHC-P, IF
- Format: Purified
- Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
- Reconstitution: Aliquot the GAD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
- Limitations: This GAD2 antibody is available for research use only.