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PIM2 Antibody

CAT: 0800-F54449-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F54449-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pim proteins (Pim-1, Pim-2 and Pim-3) are oncogene-encoded serine/threonine kinases. Pim-2 is highly homologous to Pim-1 with similar oncogenic functions. Pim-2 overexpression promotes resistance to a host of apoptotic stimuli; its expression is negatively regulated by growth factor depletion. Increased levels of Pim-2 has also been observed in certain cancers.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000
UniProt
Q9P1W9
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 277-308 from the human protein was used as the immunogen for the PIM2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC-P, WB
Purity
SAS precipitation
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PIM2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PIM2 antibody is available for research use only.
Storage Conditions
Aliquot the PIM2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the PIM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic
Image Legend
Western blot testing of human 1) K562 and 2) SW620 cell lysate with PIM2 antibody. Predicted molecular weight ~34 kDa.

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