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FADS2 Antibody

CAT: 0800-F54265-0.2MLSize: 0.2 mLDry Ice: NoHazardous: No
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CAT#:0800-F54265-0.2MLSize:0.2 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25, Immunofluorescence: 1:25, Flow cytometry: 1:25 (1x10e6 cells)
UniProt
O95864
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 79-108 from the human protein were used as the immunogen for the FADS2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P, IF, FACS
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the FADS2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This FADS2 antibody is available for research use only.
Storage Conditions
Aliquot the FADS2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the FADS2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic
Image Legend
Western blot testing of human 1) breast and 2) liver lysate with FADS2 antibody. Predicted molecular weight ~52 kDa.

UniProtKB · O95864

Acyl-CoA 6-desaturase

FADS2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95864
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FADS2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.14.19.3
Processing
—
Secondary accessions
A8K2M6, B7Z634, Q6MZQ7, Q96H07, Q96SV8, Q9H3G3, Q9Y3X4
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

Electron transportFatty acid biosynthesisFatty acid metabolismLipid biosynthesisLipid metabolismTransport

Cellular component

Endoplasmic reticulumMembrane

Molecular function

Oxidoreductase

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix

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