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C-Met Antibody

CAT: 0800-F54057-0.1MLSize: 0.1 mLDry Ice: NoHazardous: No
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CAT#:0800-F54057-0.1MLSize:0.1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000 (transfected lysate)
UniProt
P08581
Host
Mouse
Reactivity
Human
Immunogen
A human recombinant protein was used as the immunogen for this c-Met antibody.
Clonality
Monoclonal
Isotype
LgG2a
Clone
8C10-F6-C11
Applications
WB
Purity
Protein G affinity
Format
Purified
Buffer
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Reconstitution
Store the c-Met antibody at -20oC.
Limitations
This c-Met antibody is available for research use only.
Storage Conditions
Store the c-Met antibody at -20°C.
Formulation
In PBS with 50% glycerol and 0.03% ProClin 300
Applications Notes
The stated application concentrations are suggested starting points. Titration of the c-Met antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of c-Met A) transfected (partial protein) and (B) untransfected CHO-K1 cell lysate with c-Met antibody at 1:1000. Predicted molecular weight of the transfected partial: ~38 kDa.

UniProtKB · P08581

Hepatocyte growth factor receptor

MET_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P08581
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MET
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
HGF receptor
EC number
2.7.10.1
Processing
Precursor
Secondary accessions
A1L467, B5A932, E7EQ94, O60366, Q12875, Q9UDX7, Q9UPL8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Ligand

ATP-bindingNucleotide-binding

Disease

DeafnessDisease variantNon-syndromic deafnessProto-oncogene

PTM

Disulfide bondGlycoproteinPhosphoproteinUbl conjugation

Molecular function

KinaseReceptorTransferaseTyrosine-protein kinase

Cellular component

MembraneSecreted

Domain

RepeatSignalTransmembraneTransmembrane helix

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