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TOR1AIP1 Antibody / LAP1B

CAT: 0800-F53975-0.2MLSize: 0.2 mLDry Ice: NoHazardous: No
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CAT#:0800-F53975-0.2MLSize:0.2 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Torsin A interacting protein 1 / Lamin-associated protein 1B is required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-2000
UniProt
Q5JTV8
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 42-76 from the human protein was used as the immunogen for the TOR1AIP1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the TOR1AIP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TOR1AIP1 antibody is available for research use only.
Storage Conditions
Aliquot the TOR1AIP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the TOR1AIP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Rat
Image Legend
Western blot testing of mouse testis lysate with TOR1AIP1 antibody at 1:2000. Predicted molecular weight: 66 kDa.

UniProtKB · Q5JTV8

Torsin-1A-interacting protein 1

TOIP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q5JTV8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TOR1AIP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A0A0A0MSK5, A8K630, B0QZ57, Q5JTV6, Q8IZ65, Q9H8Y6, Q9HAJ1, Q9NV52, Q9Y3X5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative promoter usageAlternative splicing

Domain

Coiled coilTransmembraneTransmembrane helix

PTM

GlycoproteinIsopeptide bondOxidationPhosphoproteinUbl conjugation

Disease

Limb-girdle muscular dystrophy

Cellular component

MembraneNucleus
Product Datasheet
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