PRDM16 Antibody

• Description:

  PR domain zinc finger protein 16 binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation.

• Specifications:

  Western blot: 1:2000-4000

• UniProt:

  Q9HAZ2

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A partial recombinant protein corresponding to amino acids 779-996 from the human protein was used as the immunogen for the PRDM16 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1 k

• Clone:

  1740CT793.52.44

• Applications:

  WB

• Purity:

  Protein G affinity chromatography

• Format:

  Purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the PRDM16 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This PRDM16 antibody is available for research use only.

• Storage Conditions:

  Aliquot the PRDM16 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the PRDM16 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of human 1) Jurkat and 2) K562 cell lysate with PRDM16 antibody at 1:4000. Predicted molecular weight: 140 kDa.