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PF4 Antibody / Platelet factor 4

CAT: 0800-F53887-0.05MLSize: 0.05 mLDry Ice: NoHazardous: No
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CAT#:0800-F53887-0.05MLSize:0.05 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Platelet factor 4 is released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-2000
UniProt
P02776
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 28-59 from the human protein was used as the immunogen for the PF4 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PF4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PF4 antibody is available for research use only.
Storage Conditions
Aliquot the PF4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the PF4 antibody may be required due to differences in protocols and substrate sensitivity.
Image Legend
Western blot testing of human spleen lysate with PF4 antibody at 1:2000. Expected molecular weight: ~8/16/32 kDa (monomer/dimer/tetramer) .

UniProtKB · P02776

Platelet factor 4

PLF4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P02776
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PF4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PF-4
EC number
—
Processing
Precursor
Secondary accessions
Q53X61, Q9UC64, Q9UC65
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Chemotaxis

Molecular function

CytokineHeparin-binding

PTM

Disulfide bondPhosphoprotein

Cellular component

Secreted

Domain

Signal

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