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AIP1 Antibody / DAB2IP

CAT: 0800-F53806-0.05MLSize: 0.05 mLDry Ice: NoHazardous: No
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CAT#:0800-F53806-0.05MLSize:0.05 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ASK-interacting protein 1 functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Plays also a role in cell cycle checkpoint control; reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. [UniProt]
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1000
UniProt
Q5VWQ8
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Human recombinant protein corresponding to amino acids 782-1038 was used as the immunogen for this AIP1 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
1626CT702.263.21
Applications
WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the AIP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This AIP1 antibody is available for research use only.
Storage Conditions
Aliquot the AIP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the AIP1 antibody may be required due to differences in protocols and substrate sensitivity.
Image Legend
Western blot testing of 1) human DU-145, 2) human HepG2, 3) mouse brain and 4) HeLa cell lysate with AIP1 antibody at 1:1000. Predicted molecular weight: 132 kDa.

UniProtKB · Q5VWQ8

Disabled homolog 2-interacting protein

DAB2P_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q5VWQ8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DAB2IP
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
DAB2 interaction protein, DAB2-interacting protein
EC number
—
Processing
—
Secondary accessions
A6H8V2, A6NHI9, B0QZB1, G3XA90, Q8TDL2, Q96SE1, Q9C0C0
Protein keywords

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Biological process

AngiogenesisApoptosisCell cycleGrowth regulationImmunityInflammatory responseInnate immunityStress responseUnfolded protein response

Cellular component

Cell membraneCell projectionCytoplasmMembrane

Domain

Coiled coil

Molecular function

Developmental proteinGTPase activation

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

Disease

Tumor suppressor

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