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Nestin Antibody

CAT: 0800-F53752-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F53752-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nestin is a class VI intermediate filament protein expressed predominantly in stem cells of the neural tube but absent from virtually all differentiated CNS cells. In the CNS, nestin is downregulated upon differentiation and replaced by neurofilaments. Transient expression of nestin has been postulated as a key step committing cells to the neural differentiation pathway. Nestin expression has also been observed in pancreatic hematopoietic stem cell populations.
CAS Number
9007-83-4
UniProt
P48681
Host
Rabbit
Immunogen
A portion of amino acids 1560-1590 from the human protein was used as the immunogen for this Nestin antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC, IF, ELISA
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Nestin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Nestin antibody is available for research use only.

UniProtKB · P48681

Nestin

NEST_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P48681
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NES
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
O00552, Q3LIF5, Q5SYZ6
Protein keywords

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Domain

Coiled coil

Molecular function

Developmental protein

Cellular component

Intermediate filament

Biological process

Neurogenesis

Technical term

Proteomics identificationReference proteome

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