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Isl1 Antibody / Islet 1

CAT: 0800-F52956-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F52956-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P61372
Host
Rabbit
Reactivity
Rat
Immunogen
This mouse Isl1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 302-336 amino acids from the C-terminal region of mouse Isl1.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Isl1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Isl1 antibody is available for research use only.
Storage Conditions
Aliquot the Isl1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Isl1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Human, Chicken, Zebrafish
Image Legend
Western blot analysis of lysate from rat brain tissue lysate using Isl1 antibody at 1:1000. Predicted molecular weight ~39 kDa.

UniProtKB · P61372

Insulin gene enhancer protein ISL-1

ISL1_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P61372
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Isl1
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
Islet-1
EC number
—
Processing
—
Secondary accessions
P20663, P47894, Q812D8
Protein keywords

Technical term

3D-structureReference proteome

Molecular function

ActivatorDevelopmental proteinDNA-binding

Coding sequence diversity

Alternative splicing

Biological process

DifferentiationTranscriptionTranscription regulation

Domain

HomeoboxLIM domainRepeat

Ligand

Metal-bindingZinc

Cellular component

Nucleus

PTM

PhosphoproteinUbl conjugation

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