Wdr5 Antibody

• Description:

  Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation (By similarity) .

• Specifications:

  Western blot: 1:1000

• UniProt:

  P61965

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This mouse Wdr5 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the region of mouse Wdr5.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, ELISA

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the Wdr5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This Wdr5 antibody is available for research use only.

• Storage Conditions:

  Aliquot the Wdr5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the Wdr5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Prediction Reactivity:

  Rat

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot analysis of lysate from 1) human liver tissue and 2) mouse NIH3T3 cell line using Wdr5 antibody at 1:1000. Predicted molecular weight ~36 kDa.