SMAD1 Antibody

• Description:

  Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) . SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.

• Specifications:

  Western blot: 1:1000

• UniProt:

  Q15797

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SMAD1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 257-290 amino acids from the Central region of human SMAD1.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, ELISA

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the SMAD1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This SMAD1 antibody is available for research use only.

• Storage Conditions:

  Aliquot the SMAD1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the SMAD1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Prediction Reactivity:

  Mouse, Rat, Bovine

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot analysis of lysate from HT-1080 cell line using SMAD1 antibody; Ab was diluted at 1:1000. Predicted molecular weight: 52~60 kDa.