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Mouse Insrr Antibody

CAT: 0800-F52851-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F52851-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Insulin related receptor is a receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q9WTL4
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
This mouse Insrr antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1265-1295 amino acids from the C-terminal region of mouse Insrr.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the mouse Insrr antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This mouse Insrr antibody is available for research use only.
Storage Conditions
Aliquot the mouse Insrr antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the mouse Insrr antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of lysate from rat brain tissue using Insrr antibody at 1:1000. Expected size: ~80 kDa, 144 kDa.

UniProtKB · Q9WTL4

Insulin receptor-related protein

INSRR_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q9WTL4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Insrr
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
IRR
EC number
2.7.10.1
Processing
Precursor
Secondary accessions
B2RQC5
Protein keywords

Ligand

ATP-bindingNucleotide-binding

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinPhosphoprotein

Molecular function

KinaseReceptorTransferaseTyrosine-protein kinase

Cellular component

Membrane

Technical term

Reference proteome

Domain

RepeatSignalTransmembraneTransmembrane helix

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