OPA1 Antibody

• Description :

  Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space.

• CAS Number :

  9007-83-4

• Specifications :

  Western blot: 1:1000

• UniProt :

  O60313

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  This OPA1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 895-929 amino acids from the C-terminal region of human OPA1, form S1.

• Clonality :

  Polyclonal

• Isotype :

  Ig

• Applications :

  WB, ELISA

• Purity :

  Antigen affinity

• Format :

  Antigen affinity purified

• Buffer :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution :

  Aliquot the OPA1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations :

  This OPA1 antibody is available for research use only.

• Storage Conditions :

  Aliquot the OPA1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes :

  Titration of the OPA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Prediction Reactivity :

  Chicken, Zebrafish

• Image Legend :

  Western blot analysis of lysate from (1) HeLa cell line, (2) mouse brain and (3) rat brain tissue lysate using OPA1 antibody at 1:1000.