MERTK Antibody

• Description:

  MERTK is a member of the MER/AXL/TYRO3 receptor kinase family and a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in MERTK gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) .

• Specifications:

  Western blot: 1:1000, Immunofluorescence: 1:10-1:50, IHC (Paraffin) : 1:50-1:10, Flow Cytometry: 1:10-1:50

• UniProt:

  Q12866

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MERTK antibody was produced from rabbits immunized with a his tag recombinant protein of human MERTK.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  IHC, FACS, IF, WB, ELISA

• Purity:

  Purified

• Format:

  Purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the MERTK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This MERTK antibody is available for research use only.

• Storage Conditions:

  Aliquot the MERTK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the MERTK antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Fluorescent image of U251 cell stained with MERTK antibody at 1:25. MERTK immunoreactivity is localized to vesicles.