Products for Research Use Only
RegisterLogin

BTK Antibody

CAT: 0800-F50702-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-F50702-0.4MLSize:0.4 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
BTK plays a crucial role in B-cell ontogeny. This protein transiently phosphorylates GTF2I on tyrosine residues in response to B-cell receptor cross-linking. Defects in BTK are the cause of X-linked agammaglobulinemia type 1 (XLA) . XLA is a humoral immunodeficiency disease which results in developmental defects in the maturation pathway of B-cells. Affected boys have normal levels of pre-B-cells in their bone marrow but virtually no circulating mature B-lymphocytes. This results in a lack of immunoglobulins of all classes and leads to recurrent bacterial infections like otitis, conjunctivitis, dermatitis, sinusitis or fatal sepsis or meningitis within the first years of life.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Immunofluorescence: 1:10-1:50, IHC (Paraffin) : 1:50-1:100
UniProt
Q06187
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 209-239 from the human protein was used as the immunogen for this BTK antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IF, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the BTK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This BTK antibody is available for research use only.
Storage Conditions
Aliquot the BTK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the BTK antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Confocal immunofluorescent analysis of BTK antibody with 293 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green) . DAPI was used as a nuclear counterstain (blue) .

Related Products

CatalogName
RQ4624NONO Antibody / p54nrb Antibody
F53954-0.2MLAntibody
F53954-0.05MLAntibody
F53952-0.2MLAntibody
F53952-0.05MLAntibody
V8674-20UGInhibin alpha Antibody / INHA antibody
V8674SAF-100UGInhibin alpha Antibody / INHA antibody
V8674-100UGInhibin alpha Antibody / INHA antibody
R20161SAF-250UGLambda Light Chain Antibody / Lambda Antibody
R20179SAF-250UGLambda Light Chain Antibody / Lambda Antibody

Alternative Products

CatalogName
MBS8529199-01H2B Antibody Antibody
MBS8513599-01CD11b Antibody Antibody
MBS850197-01Antibody to IGFBP2 Antibody
DF8746-01ASAP1 antibody Antibody
E36403ZNF98 Antibody Antibody
GWB-250026Lck antibody Antibody
E8M1007-4HSP60 Antibody Antibody
MBS9403836-01SZT2 Antibody Antibody
LSMab09882anti-Antibody^Polyclonal antibody control antibody
GWB-5C6547MAD1L1 antibody [9B10] Antibody

Popular Products