Products for Research Use Only
RegisterLogin

MUSK Antibody

CAT: 0800-F50652-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-F50652-0.08MLSize:0.08 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
CAS Number
9007-83-4
UniProt
O15146
Host
Rabbit
Immunogen
A portion of amino acids 829-859 from the human protein was used as the immunogen for this MUSK antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, FACS, ELISA
Format
Purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the MUSK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This MUSK antibody is available for research use only.

UniProtKB · O15146

Muscle, skeletal receptor tyrosine-protein kinase

MUSK_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O15146
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MUSK
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.10.1
Processing
Precursor
Secondary accessions
Q32MJ8, Q32MJ9, Q5VZW7, Q5VZW8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Cellular component

Cell membraneMembranePostsynaptic cell membraneSynapse

Disease

Congenital myasthenic syndromeDisease variant

Molecular function

Developmental proteinKinaseMuscle proteinReceptorTransferaseTyrosine-protein kinase

Biological process

Differentiation

PTM

Disulfide bondGlycoproteinPhosphoproteinUbl conjugation

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Related Products

CatalogName
RQ4624NONO Antibody / p54nrb Antibody
F53954-0.2MLAntibody
F53954-0.05MLAntibody
F53952-0.2MLAntibody
F53952-0.05MLAntibody
V8674-20UGInhibin alpha Antibody / INHA antibody
V8674SAF-100UGInhibin alpha Antibody / INHA antibody
V8674-100UGInhibin alpha Antibody / INHA antibody
R20161SAF-250UGLambda Light Chain Antibody / Lambda Antibody
R30971B-Actin Antibody / Beta Actin Antibody

Alternative Products

CatalogName
10R-2058MuSK antibody

Popular Products