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VEGFR2 Antibody

CAT: 0800-F50626-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F50626-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KDR (FLK1) is a receptor for VEGF or VEGFC. This protein has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Immunofluorescence: 1:10-1:50, Flow Cytometry: 1:10-1:50, IHC (Paraffin) : 1:50-1:100
UniProt
P35968
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 1326-1356 from the human protein was used as the immunogen for this VEGFR2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IF, FACS, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the VEGFR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This VEGFR2 antibody is available for research use only.
Storage Conditions
Aliquot the VEGFR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the VEGFR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic and cell surface
Image Legend
Confocal immunofluorescent analysis of VEGFR2 antibody with HeLa cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green) . DAPI was used as a nuclear counterstain (blue) .

UniProtKB · P35968

Vascular endothelial growth factor receptor 2

VGFR2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35968
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KDR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
VEGFR-2
EC number
2.7.10.1
Processing
Precursor
Secondary accessions
A2RRS0, B5A925, C5IFA0, O60723, Q14178
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

AngiogenesisDifferentiationHost-virus interaction

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell junctionCell membraneCytoplasmCytoplasmic vesicleEndoplasmic reticulumEndosomeMembraneNucleusSecreted

Molecular function

Developmental proteinKinaseReceptorTransferaseTyrosine-protein kinase

PTM

Disulfide bondGlycoproteinPhosphoproteinUbl conjugation

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

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