Macrophage Colony Stimulating Factor 1 Receptor Antibody (CSF1R)

Macrophage Colony Stimulating Factor 1 Receptor Antibody (CSF1R)

• Description: CSF1R is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. This protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in the gene encoding CSF1R have been associated with a predisposition to myeloid malignancy.
• CAS Number: 9007-83-4
• UniProt: P07333
• Host: Rabbit
• Immunogen: A portion of amino acids 940-971 from the human protein was used as the immunogen for this CSF1R antibody.
• Clonality: Polyclonal
• Isotype: Ig
• Applications: WB, FACS, IHC, ELISA
• Format: Purified
• Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Reconstitution: Aliquot the CSF1R antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This CSF1R antibody is available for research use only.