PCSK9 Antibody

• Description:

  PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.

• Specifications:

  Flow Cytometry: 1:25, IHC (Paraffin) : 1:25, Western blot: 1:1000

• UniProt:

  Q8NBP7

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 144-173 from the human protein was used as the immunogen for this PCSK9 antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  FACS, IHC, WB, ELISA

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS pH 7.4 with 0.09% sodium azide

• Reconstitution:

  Aliquot the PCSK9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This PCSK9 antibody is available for research use only.

• Storage Conditions:

  Aliquot the PCSK9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the PCSK9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot analysis of lysate from HeLa cell line using PCSK9 antibody. Predicted size: Pro/mature ~74/64 kDa