PCSK9 Antibody

• Description :

  PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.

• Specifications :

  Flow Cytometry: 1:25, IHC (Paraffin) : 1:25, Western blot: 1:1000

• UniProt :

  Q8NBP7

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  A portion of amino acids 144-173 from the human protein was used as the immunogen for this PCSK9 antibody.

• Clonality :

  Polyclonal

• Isotype :

  Ig

• Applications :

  FACS, IHC, WB, ELISA

• Purity :

  Antigen affinity

• Format :

  Antigen affinity purified

• Buffer :

  In 1X PBS pH 7.4 with 0.09% sodium azide

• Reconstitution :

  Aliquot the PCSK9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations :

  This PCSK9 antibody is available for research use only.

• Storage Conditions :

  Aliquot the PCSK9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes :

  Titration of the PCSK9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number :

  9007-83-4

• Image Legend :

  Western blot analysis of lysate from HeLa cell line using PCSK9 antibody. Predicted size: Pro/mature ~74/64 kDa