Aurora-C Antibody (AURKC)

Aurora-C Antibody (AURKC)

• Description: Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
• CAS Number: 9007-83-4
• UniProt: Q9UQB9
• Host: Rabbit
• Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this Aurora-C antibody.
• Clonality: Polyclonal
• Isotype: Ig
• Applications: WB, ELISA
• Format: Purified
• Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Reconstitution: Aliquot the Aurora-C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This Aurora-C antibody is available for research use only.