Products for Research Use Only
RegisterLogin

IL1R1 Antibody

CAT: 0800-F49605-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-F49605-0.4MLSize:0.4 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
IL1R is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. IL1R is a receptor for interleukin 1 family member 9 (IL1F9) . Binding to the agonist leads to the activation of NF-kappa-B. The gene for this protein and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P14778
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 474-503 from human IL-1 Receptor type 1 was used as the immunogen for this IL1R1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the IL1R1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This IL1R1 antibody is available for research use only.
Storage Conditions
Aliquot the IL1R1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the IL1R1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Rat
Image Legend
Western blot analysis of IL1R1 antibody and HL-60 lysate. Predicted molecular weight 60-65 kDa.

UniProtKB · P14778

Interleukin-1 receptor type 1

IL1R1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P14778
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL1R1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IL-1R-1, IL-1RT-1, IL-1RT1
EC number
3.2.2.6
Processing
Precursor
Secondary accessions
Q587I7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell membraneMembraneSecreted

Disease

Disease variant

PTM

Disulfide bondGlycoproteinPhosphoprotein

Molecular function

HydrolaseReceptor

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Biological process

Inflammatory response

Ligand

NAD

Related Products

CatalogName
F54851-0.08MLIL1RN Antibody / IL1RA / Interleukin-1 Receptor Antagonist
RQ6530Interleukin-1 Receptor Antagonist Antibody / IL1RA / IL1RN
F54851-0.4MLIL1RN Antibody / IL1RA / Interleukin-1 Receptor Antagonist
F54852-0.4MLInterleukin-1 Receptor Antagonist Antibody / IL1RA / IL1RN
RQ6425Il1ra Antibody / Interleukin-1 receptor antagonist / Il1rn
F54852-0.08MLInterleukin-1 Receptor Antagonist Antibody / IL1RA / IL1RN
R32852IL1RA Antibody / Interleukin-1 Receptor Antagonist / IL1RN
F41147-0.08MLIL1R2 Antibody
F41147-0.4MLIL1R2 Antibody
N1108-100UGIL1RL1 Antibody

Alternative Products

CatalogName
MBS7123252-01IL1R1 Antibody

Popular Products