ABCB7 Antibody

ABCB7 Antibody

• Description: The membrane-associated protein ABCB7 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia.
• CAS Number: 9007-83-4
• UniProt: O75027
• Host: Rabbit
• Immunogen: A portion of amino acids 718-746 from the human protein was used as the immunogen for this ABCB7 antibody.
• Clonality: Polyclonal
• Isotype: Ig
• Applications: WB, IHC, ELISA
• Format: Purified
• Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Reconstitution: Aliquot the ABCB7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This ABCB7 antibody is available for research use only.