Products for Research Use Only
RegisterLogin

XRCC1 Antibody

CAT: 0800-F49231-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-F49231-0.4MLSize:0.4 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
CAS Number
9007-83-4
Specifications
Immunofluorescence: 1:25, Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100, Flow Cytometry: 1:10-1:50
UniProt
P18887
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 407-435 from the human protein was used as the immunogen for this XRCC1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, FACS, IF, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the XRCC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This XRCC1 antibody is available for research use only.
Storage Conditions
Aliquot the XRCC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the XRCC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Nuclear
Image Legend
Immunofluorescent analysis of A549 cells using XRCC1 antibody at 1:25. Alexa Fluor 488-conjugated secondary was used (green) . Cytoplasmic actin was counterstained with Dylight Fluor 554 conjugated Phalloidin (red) .

Related Products

CatalogName
RQ6077XRCC2 Antibody
V4943SAF-100UGXRCC5 Antibody
V4944-100UGXRCC5 Antibody
RQ5784Xrcc4 Antibody
V4943-100UGXRCC5 Antibody
V8167-20UGXRCC3 Antibody
V4940-100UGXRCC5 Antibody
V4942-100UGXRCC5 Antibody
F47295-0.08MLXRCC2 Antibody
V8167SAF-100UGXRCC3 Antibody

Alternative Products

CatalogName
70R-30836XRCC1 antibody

Popular Products