Products for Research Use Only
RegisterLogin

SMAD6 Antibody

CAT: 0800-F49135-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-F49135-0.08MLSize:0.08 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SMAD6 acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions. [UniProt]
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
O43541
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 358-386 from the human protein was used as the immunogen for this SMAD6 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Store at 4oC for up to one month. For long term, aliquot the SMAD6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SMAD6 antibody is available for research use only.
Storage Conditions
Store at 4°C for up to one month. For long term, aliquot the SMAD6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the SMAD6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Mouse
Image Legend
Western blot testing of human lung lysate with SMAD6 antibody. Observed molecular weight: 50~60 kDa.

Related Products

CatalogName
RQ4044SMAD1 / SMAD5 Antibody
R32238SMAD Antibody [SMAD1-5]
F50739-0.4MLSMAD4 Antibody
F52570-0.08MLSMAD1 Antibody
R32172SMAD3 Antibody
V8414-100UGSMAD4 Antibody
V8318-20UGSMAD4 Antibody
R34284-100UGSMAD9 Antibody
V4035SAF-100UGSMAD4 Antibody
V4575SAF-100UGSMAD4 Antibody

Alternative Products

CatalogName
70R-50030SMAD6 antibody

Popular Products